Mixed Meal Model in Type 1 Diabetes
نویسندگان
چکیده
منابع مشابه
A Novel Insulin/Glucose Model after a Mixed-Meal Test in Patients with Type 1 Diabetes on Insulin Pump Therapy
Current closed-loop insulin delivery methods stem from sophisticated models of the glucose-insulin (G/I) system, mostly based on complex studies employing glucose tracer technology. We tested the performance of a new minimal model (GLUKINSLOOP 2.0) of the G/I system to characterize the glucose and insulin dynamics during multiple mixed meal tests (MMT) of different sizes in patients with type 1...
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BACKGROUND Fully automated artificial pancreas systems require meal detectors to supplement blood glucose level regulation, where false meal detections can cause unnecessary insulin delivery with potentially fatal consequences, and missed detections may cause the patient to experience extreme hyperglycemia. Most existing meal detectors monitor various measures of glucose rate-of-change to detec...
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Mixed-meal tolerance tests (MMTTs) are used in clinical trials to evaluate b-cell function in patients with newonset type 1 diabetes (1,2). Some trials use a 4-h MMTT, whereas others use an abbreviated (2-h) protocol to reduce investigator and subject burden. In the T1DAL (Inducing Remission in Type 1 Diabetes With Alefacept) trial of patients with new-onset type 1 diabetes, the primary analysi...
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BACKGROUND The pathophysiology of type2 diabetes involves both insulin resistance and poor beta cell function. Studies have been done in several populations to assess the relative importance of these mechanisms in individual patients. In our environment studies to assess beta cell function have been done with glucagon stimulation or an oral glucose tolerance test. This study was done to assess ...
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The extent and time course of suppression of endogenous glucose production (EGP) in type 2 diabetes after a mixed meal have been determined using a new tracer methodology. Groups of age-, sex-, and weight-matched normal controls (n = 8) and diet-controlled type 2 diabetic subjects (n = 8) were studied after ingesting a standard mixed meal (550 kcal; 67% carbohydrate, 19% fat, 14% protein). Ther...
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ژورنال
عنوان ژورنال: Transactions of the Institute of Systems, Control and Information Engineers
سال: 2017
ISSN: 1342-5668,2185-811X
DOI: 10.5687/iscie.30.286